Cross margin vs isolated margin
Cross margin is the default and the most capital-efficient: all cross positions share one collateral pool, and unrealised profit on one position is immediately usable as initial margin for another. The cost is contagion — a cross liquidation reaches every cross position and, if there are no isolated positions, can leave the account at zero equity.
Isolated margin constrains an asset's collateral to that asset. A liquidation there does not touch cross positions or other isolated positions, and vice versa. Isolated positions also allow margin to be added or removed after opening, unless the asset is 'strict isolated', where margin can only leave proportionally as the position closes.